I'm with Liberty Wellsian on this. I too argued all for keeping the Civic Center open space on Washington Square and the Library block but am I 100% against turning the block north of Little America into a huge park. As has been mentioned it's a huge wasn't of TOD potential.
While I like Palladio's massing of the block I do think an E/W road or pedestrian access should be around mid-block, that provides an inviting corridor for people crossing the street from the Trax Platform at mid-block. It could also preserve a huge number of trees that are currently along that center sidewalk. Maybe the block from north to south gets split three times, mid block pedestrian, and a narrow street on the north and the south, and maybe split twice east to west, as Palladio's massing shows. I do think a park could work in the middle of the block, and would be highly utilized due to the density surrounding it.
It looks nowhere as cool as the massing that Palladio did, but here's a stab at the layout. This actually splits it up into twelve smaller blocks.
Blue= Office
Red = Residential
Purple = mixed use
Orange = Hotel
Most of the office and residential would have some street level retail, as to make it more of a retail are. While one way streets are not a benefits to retail I think for one block it may be beneficial to make these for streets one ways, that allows for reduced street width while still providing at least one side of parking, or they could be two way with one side of parking, similar to the southern section of Regent St.