HOUSTON | MD Anderson Ambulatory Care Buildings 2 & 3 | FT | 17 & 19 FLOORS

[Wattleigh]

These buildings were discussed during the May 4-5 meeting of the UT System Board of Regents

A large patient tower to be built elsewhere on the campus was also mentioned during this meeting, though there are few details on it at the moment.

Relevant text from the agenda.

Consistent with the institution's Master Facilities Framework 2030, U. T. M. D. Anderson Cancer Center is proposing to construct two new buildings, Ambulatory Clinical Building 2 (2ACB) and Ambulatory Clinical Building 3 (3ACB). These new buildings are to be located on the institution's Texas Medical Center campus (TMC Campus), south of Holcombe Boulevard and bounded by Pressler Street on the south, Richard J.V. Johnson Avenue on the east, and Fannin Street on the west.

While the project includes two separate buildings with integrated parking garages, 2ACB and 3ACB are expected to be joined at the podium level to form one contiguous ambulatory treatment facility (2/3 ACB) that is proximate to and interconnected with the existing Lowry and Peggy Mays Clinic and the Dan L. Duncan Building. Overall, the 2/3 ACB facility is anticipated to consist of approximately 3,300,000 gross square feet (GSF).

2ACB will consist of 950,000 GSF of clinical and departmental program space located on seventeen floors above grade and 550,000 GSF of parking located on three floors below grade as well as a central parking structure. In total, there will be 1,500 parking spaces added on five levels. 3ACB will consist of 1,500,000 GSF of clinical and departmental program space located on nineteen floors above grade and 300,000 GSF of below-grade parking adding another 785 parking spaces.

The project is also expected to include the construction of two seven-story connectors that will complete a circulation route between 2/3 ACB, the Mays Clinic, and the Duncan Building, forming a complete quadrangle around the central parking structure. The top of the parking structure will align with the existing exterior plaza decks of the Mays Clinic and the Duncan Building to form a raised exterior garden.

If this recommendation is approved, the project is expected to proceed with requested inclusion in the Capital Improvement Program (CIP) in August 2023, design development approval in May 2024, construction start in November 2024, and substantial completion in December 2027.

[Wattleigh]

The two buildings apparently have grown substantially. Now 22 & 26 floors. Based on the comments made by Tower Spotter below, they would be 408' & 438' or so, sharing a common garage, with three underground levels. It will also be adjacent to the TMC Transit Center for the bus & METRORail Red line.

Info from Highrise Tower on HAIF - June 2

In the Texas Higher Education Coordinating Board Capital Expenditure Plan Report dated September 2022; there is talk about the forthcoming MD Anderson Ambulatory Clinical Buildings 2 and 3.

Both in footprint, and dollar value, these 2 buildings are very impressive. Believe it's 2.5 million square feet and nearly $2.5 billion in cost.

The buildings are said to start construction in July 2024.

The MD Anderson Prairie (the former site of the Prudential Building and a surface lot will be removed in the process. It will connect to the existing low-rise Duncan Building & Mays Clinic.

Additional photos from Highrise Tower of that site.





Post on June 23 from the same user on HAIF

Out for bidding!!

The taller one is set to be 26 stories with a height of 438 feet. At full build-out it will be 3.1 million square feet, Phase 1 includes 1.9 million square feet.

This will be massive, imposing at street level. The METRORail Red Line will go right next to it when passing Fannin Street. This also extends the Holcombe Blvd skyline!

MD Anderson does it again. Let's go!!

[Zapatan]

Holy cow, the scale of that thing.

[bilbao58]

Holy crap! It's HUGE.

[Wattleigh]

Additional information c/o Paco Jones on HAIF (8/26/24)

I believe a general contractor has been chosen but the announcement has not been made yet. Architect is CannonDesign.

BOTH towers will start in 2025 per info from Highrise Tower on HAIF.



He also observes via the massing diagrams in a report...

Cool drawings of the massing and height these towers will have.

In comparison with the Holcombe Blvd skyline. It will be the tallest building on Holcombe!



With the rest of the TMC:

[Wattleigh]

Lines are being marked off on site - c/o Highrise Tower on HAIF

[Wattleigh]

Plan for this site appears to have been revised - copying from the general Houston highrise thread...

Originally Posted by Wattleigh

MD Anderson PCB1

Site plan c/o Houston Business Journal



This will be a substantial structure - 1.8msf and will be constructed with separate Radiation Oncology Building at the same time. Total cost: $ 2.5 billion.

Some equipment is being moved onsite at this time.

Site overview c/o hindesky on HAIF











Ground level photos c/o Highrise Tower on HAIF

Starting to clear the MD Anderson Prairie - c/o Highrise Tower on HAIF

[Wattleigh]

Looks like there is some excavation work already taking place - c/o Highrise Tower on HAIF

[Wattleigh]

Project is likely taller than before - now a 25-story tower and therapeutic radiation center

https://hoodline.com/2026/05/md-anderson...ower-set-to-shake-up-houston-med-center/

MD Anderson’s $2.9 Billion Cancer Tower Set To Shake Up Houston Med Center

By Maddie Taylor Hartley
Published on May 26, 2026

The University of Texas MD Anderson Cancer Center just got the green light for one of the biggest projects in the Texas Medical Center, a patient care expansion now valued at just over $2.9 billion. Regents signed off earlier this week on the final stages of Patient Care Building 1, approving a 25-floor clinical tower and a standalone Therapeutic Radiation Center that will boost both inpatient capacity and outpatient clinics. The new tower is designed to help untangle patient flow across MD Anderson’s main campus, where getting from one appointment to the next can feel like running a maze on a tight schedule.


Funding And The Regents' Vote
According to The University of Texas System, the Board of Regents amended its capital improvement program this week to boost the project budget and add the final phases to the system capital plan, moving the total estimate to roughly $3.0 billion. Board materials show MD Anderson plans to put in about $1.64 billion from hospital revenues, while the system would issue roughly $1.2 billion in Revenue Financing System bonds to cover the rest.

Project Scope And Design
MD Anderson’s own planning materials describe Patient Care Building 1 as roughly 1.74 million to 1.8 million square feet, with 25 floors above ground and two basement levels. The space is laid out for disease-specific clinics, infusion therapy, expanded inpatient units, and diagnostic and treatment suites. As outlined by UT MD Anderson, the design leans heavily into patient experience, with planned skybridges, terraces, and integrated wayfinding so patients and families spend less time wandering hallways and more time actually getting care.

[Wattleigh]

This one is moving pretty quick - c/o Highrise Tower on HAIF

[Wattleigh]

Very quickly it seems - c/o Brookyln173 on HAIF







And it looks like a formal groundbreaking ceremony was held this week - per Highrise Tower on HAIF