.
The same eBay seller also has this 1927 negative up for sale.
1927 photo Celluloid Negative Los Angeles California Street Scene LA Library Trolley CAR.
eBay
The location is too obvious
(that's the Los Angeles Public Library on the right) to be a
mystery location so I decided to run with it myself.
The photographer is looking southwest from what appears to have been the middle of S. Grand Avenue.
Initially I was simply going to say the photographer was standing near the base of the Edison Building but I don't think it was there yet. (but it was probably under construction)
Yours truly has placed a
red dot where I believe the photographer was standing.

photograph is dated 1930
water & power archive
The
Edison Building opened on March 20, 1931.
.