Yeah. There are two major border crossings with Quebec but only one of them allows access to main Canadian highway system:
The other just extends a little ways along Quebec's Lower North Shore. In this area, Corner Brook tends to be the main destination for healthcare, shopping, etc. as they have no highway access to the rest of Quebec.
The ferry link you see above is the main passenger link between NL and Labrador. It actually docks in Blanc Sablon, on the Quebec side. On our side it normally docks in St. Barbe, as pictured, but when the strait is jammed with ice it often gets diverted to Corner Brook instead.