Pfizer's kinda cute, I like the patterning on its facade- I'd consider giving that one the 425 Park Avenue treatment. Keep some of the existing structure and make it bigger, give it a new facade that's a sleek and updated interpretation of what it had before. So an upsize and upgrade, pretty much.
As for the building swap, somebody mentioned 300 Park Avenue as a possible candidate- I don't think that one's landmarked. And I think 300 Park is right close to that church on Park Avenue (can't remember the name) which is apparently planning to sell its air rights.
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"Build me to the heavens, and Life never stops"
"Live as if the world were as it should be, to show it what it can be"
-Angel
"Prayers are fleeting and wars are forgotten, but what is built endures"
-Ambassador DeLenn, Babylon 5
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