The Arizona Science center in downtown Phx:
Like a lot of brutalism, it looks cool as a form, or as an overgrown piece of sculpture, but its an abomination as far as its relationship to the street goes.
It was designed by
Antoine Predock
Predock also did the somewhat similar Nelson Fine Arts Center in Tempe at ASU:
Photos that weren't mine are from Visionsinphoto.com & architectureweek