[GlassCity]

Canada: Montreal
British Columbia: Victoria (strong #2 and a relevant centre)
Alberta: Red Deer or Lethbridge (assuming Calgary and Edmonton are 1a and 1b)
Saskatchewan: Prince Albert (assuming Saskatoon and Regina are 1a and 1b)
Manitoba: Brandon (strong #2, but far far behind Winnipeg)
Ontario: Ottawa (strong #2, but in unique position as federal capital)
Quebec: Quebec City (strong #2, relevant centre)
New Brunswick: Saint John? (as a total outsider, Moncton, Saint John, and Fredericton are all close enough that it feels like it could be a 1a, 1b, and 1c type of thing)
PEI: Summerside
Nova Scotia: Sydney?
Newfoundland and Labrador: Corner Brook (far far behind St. John's)
Yukon: Dawson City (strong #2)
Northwest Territories: Hay River/Inuvik
Nunavut: Rankin Inlet/Arviat?

Metro Vancouver bonus: Surrey (strong #2 after Vancouver)

This would be fun to split into a tier system in a spreadsheet sometime.