Neglect for Sears. There's been some rumours, but I fear it is destined to the same fate as Travellers in another ten years.
What would be on my list:
Leader Building
Guaranty Building
Old Post Office
Hotel Saskatchewan
Northern Crown Building
Dominion Government Building, Federal Building
Balfour Apartments
Strathdee Warehouse
Canada Life Assurance Building
Sherwood Department Store
I would vote for the SaskPower Building hands down if it was in the list. It is unique to Regina.
• Video Link
Worth the 30 minutes of your time if you haven't watched it yet.
On this list, it is between Canada Life, Leader and Dominion. Dominion is such a treasure and really a quite unique structure with it's Art Deco style and pyramid form. A real beauty, especially up close. Canada Life is a little grander than Leader, but there is something about Leader's mid-block setting that is special. But those are three special buildings. Might be able to make a case that the Old Post Office building (Prince Edward) should be on the list as well.