jmancuso posted one of my absolute favorites - the Niagara-Mohawk Building in Syracuse, NY.
Some examples of Art Deco from Northeast Ohio:
One of the four Guardians of Transportation and the Ohio Bell Huron Building:
Akron's First National Tower:
Youngstown's Metropolitan Bank Tower:
And one of my favorites from Cincinnati, the Orchid Room at the Netherland Hilton Hotel: