[aaron38]

I agree with the tumor comment for the second design. If you're going to design an organic building, then you have to follow the laws of organisms. So when a building bulges and curves, it looks muscular and not fat.
And if you design an organic building that looks like it has diseases and cancer, no one is going to want to live in it.

I read an article once about plans for a long term nuclear storage area, that would be toxic for thousands of years. They wanted warning signs that would span all languages and cultures, something that would still say "Stay the hell out!" 5000 years from now. One of the designs was similar to this. An organic structure that twisted and bulged, looking obviously sick.
Cancerous buildings are a bad idea.